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    CG4049 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37860, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4049provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034976
    Locus tag
    Dmel_CG4049
    See related
    AllianceGenome:FB:FBgn0034976
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Arip4; BEST:LD04705; Dmel\CG4049
    Summary
    Predicted to enable ATP-dependent chromatin remodeler activity and transcription coregulator activity. Predicted to be involved in chromatin organization. Predicted to be active in nucleus. Orthologous to human RAD54L2 (RAD54 like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4049 in Genome Data Viewer
    Location:
    60B10-60B10; 2-106 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24107087..24114292, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19994610..20001815, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene genghis khan Neighboring gene enoki mushroom Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A P element has induced intron formation in Drosophila. Nouaud D, et al. Mol Biol Evol, 1999 Nov. PMID 10555281
    2. CSB-independent, XPC-dependent transcription-coupled repair in Drosophila. Deger N, et al. Proc Natl Acad Sci U S A, 2022 Mar 1. PMID 35217627, Free PMC Article
    3. The XNP remodeler targets dynamic chromatin in Drosophila. Schneiderman JI, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19706533, Free PMC Article
    4. The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes. Nikalayevich E, et al. J Cell Sci, 2015 Feb 1. PMID 25501812, Free PMC Article
    5. The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. Svetec N, et al. PLoS Genet, 2016 Mar. PMID 26950216, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent chromatin remodeler activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4049-PA
    R-gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24107087..24114292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138041.3 → NP_611885.3  uncharacterized protein Dmel_CG4049 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611885.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1A8
      Conserved Domains (3) summary
      cd00046
      Location:420 → 598
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:958 → 1093
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00176
      Location:394 → 730
      SNF2_N; SNF2 family N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1A8 Q9W1A8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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