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    Osi17 Osiris 17 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40774, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Osi17provided by FlyBase
    Official Full Name
    Osiris 17provided by FlyBase
    Primary source
    FLYBASE:FBgn0037427
    Locus tag
    Dmel_CG15598
    See related
    AllianceGenome:FB:FBgn0037427
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15598; Dmel\CG15598; mdcds_43703
    Summary
    Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in several structures, including embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; embryonic hypopharynx; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Osi17 in Genome Data Viewer
    Location:
    83E2-83E3; 3-47.5 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6311772..6327308)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2137494..2153030)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Osiris 18 Neighboring gene Osiris 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Osiris17 is essential for stable integrin localization and function during insect wing epithelia remodeling. Dong W, et al. Int J Biol Macromol, 2024 Apr. PMID 38367779
    2. Tracheal expression of Osiris gene family in Drosophila. Scholl A, et al. Gene Expr Patterns, 2018 Jun. PMID 29548969
    3. Conserved roles of Osiris genes in insect development, polymorphism and protection. Smith CR, et al. J Evol Biol, 2018 Apr. PMID 29322640
    4. Osiris gene family defines the cuticle nanopatterns of Drosophila. Sun Z, et al. Genetics, 2024 Jun 5. PMID 38652268, Free PMC Article
    5. Evolution of a large, conserved, and syntenic gene family in insects. Shah N, et al. G3 (Bethesda), 2012 Feb. PMID 22384409, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    osiris 17
    Names
    CG15598-PA
    CG15598-PB
    CG15598-PC
    CG15598-PD
    Osi17-PA
    Osi17-PB
    Osi17-PC
    Osi17-PD
    osiris

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6311772..6327308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275379.1 → NP_001262308.1  osiris 17, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262308.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGL7
      Conserved Domains (3) summary
      pfam07898
      Location:180 → 270
      DUF1676; Protein of unknown function (DUF1676)
      cl09111
      Location:603 → 680
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl11657
      Location:661 → 745
      DM4_12; DM4/DM12 family

    2. NM_001275377.1 → NP_001262306.1  osiris 17, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262306.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MST0, Q9VNN9
      Conserved Domains (3) summary
      pfam07898
      Location:180 → 270
      DUF1676; Protein of unknown function (DUF1676)
      cl09111
      Location:501 → 578
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl11657
      Location:559 → 643
      DM4_12; DM4/DM12 family

    3. NM_001275378.1 → NP_001262307.1  osiris 17, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGL7
      Conserved Domains (3) summary
      pfam07898
      Location:180 → 270
      DUF1676; Protein of unknown function (DUF1676)
      cl09111
      Location:603 → 680
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl11657
      Location:661 → 745
      DM4_12; DM4/DM12 family

    4. NM_141381.3 → NP_649638.2  osiris 17, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649638.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MST0, Q9VNN9
      Related
      FBpp0078259
      Conserved Domains (3) summary
      pfam07898
      Location:180 → 270
      DUF1676; Protein of unknown function (DUF1676)
      cl09111
      Location:501 → 578
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl11657
      Location:559 → 643
      DM4_12; DM4/DM12 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KGL7 A0A0B4KGL7
    Q9VNN9 Q9VNN9

    Gene LinkOut

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