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    CG15279 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34863, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15279provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028886
    Locus tag
    Dmel_CG15279
    See related
    AllianceGenome:FB:FBgn0028886
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0149848.9; BG:DS03431.1; Dmel\CG15279; DmNAT6; DS03431.1
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity; amino acid:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Predicted to be involved in glycine import across plasma membrane; neurotransmitter transport; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult abdomen; adult head; and adult thorax. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15279 in Genome Data Viewer
    Location:
    35B6-35B6; 2-50 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (14844993..14851749, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (14844993..14851749, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43805 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct functions of Mst77F and protamines in nuclear shaping and chromatin condensation during Drosophila spermiogenesis. Rathke C, et al. Eur J Cell Biol, 2010 Apr. PMID 20138392
    2. Comparative sequence analysis and tissue localization of members of the SLC6 family of transporters in adult Drosophila melanogaster. Thimgan MS, et al. J Exp Biol, 2006 Sep. PMID 16916974
    3. The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique d-amino acid affinity and mediates gut and brain functions. Miller MM, et al. Insect Biochem Mol Biol, 2008 Oct. PMID 18718864, Free PMC Article
    4. Metabolite transport across the mammalian and insect brain diffusion barriers. Weiler A, et al. Neurobiol Dis, 2017 Nov. PMID 28237316
    5. A transcriptomics assessment of oxygen-temperature interactions reveals novel candidate genes underlying variation in thermal tolerance and survival. Boardman L, et al. J Insect Physiol, 2018 Apr. PMID 29038013

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid:monoatomic cation symporter activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables amino acid:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables neurotransmitter transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    involved_in glycine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neurotransmitter transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15279-PA
    CG15279-PB
    CG15279-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      14844993..14851749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165093.2 → NP_723885.1  uncharacterized protein Dmel_CG15279, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6CLF8, Q9VJR4
      Related
      FBpp0080247
      Conserved Domains (1) summary
      cl00456
      Location:50 → 598
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. NM_001014484.2 → NP_001014484.2  uncharacterized protein Dmel_CG15279, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014484.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6CLF8, Q1WWD3, Q59DZ2
      Conserved Domains (2) summary
      cd10324
      Location:51 → 532
      SLC6sbd; Solute carrier 6 family, neurotransmitter transporters; solute-binding domain
      cl23746
      Location:520 → 573
      HCO3_cotransp; HCO3- transporter family

    3. NM_135882.4 → NP_609726.1  uncharacterized protein Dmel_CG15279, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609726.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6CLF8, Q9VJR4
      Related
      FBpp0080248
      Conserved Domains (1) summary
      cl00456
      Location:50 → 598
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q59DZ2 Q59DZ2
    Q9VJR4 Q9VJR4

    Gene LinkOut

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