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    CG9514 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32418, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9514provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030592
    Locus tag
    Dmel_CG9514
    See related
    AllianceGenome:FB:FBgn0030592
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dm GMCdelta1; Dmel\CG9514
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be involved in ecdysteroid metabolic process. Is expressed in several structures, including adult head; anlage in statu nascendi; antennal anlage; antennal primordium; and head epidermis primordium. Orthologous to human CHDH (choline dehydrogenase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9514 in Genome Data Viewer
    Location:
    13A1-13A1; 1-49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14885952..14896891, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14779985..14790924, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Flotillin 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene fezzik

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of ecdysteroid signalling during Drosophila development: identification, characterization and modelling of ecdysone oxidase, an enzyme involved in control of ligand concentration. Takeuchi H, et al. Biochem J, 2005 Aug 1. PMID 15813704, Free PMC Article
    2. Complexities of recapitulating polygenic effects in natural populations: replication of genetic effects on wing shape in artificially selected and wild-caught populations of Drosophila melanogaster. Pelletier K, et al. Genetics, 2023 Jul 6. PMID 36961731, Free PMC Article
    3. Expansion and evolution of insect GMC oxidoreductases. Iida K, et al. BMC Evol Biol, 2007 May 11. PMID 17498303, Free PMC Article
    4. Identification of conserved transcriptome features between humans and Drosophila in the aging brain utilizing machine learning on combined data from the NIH Sequence Read Archive. Webb JL, et al. PLoS One, 2021. PMID 34379632, Free PMC Article
    5. Systematic image-driven analysis of the spatial Drosophila embryonic expression landscape. Frise E, et al. Mol Syst Biol, 2010. PMID 20087342, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables choline dehydrogenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on CH-OH group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ecdysteroid metabolic process IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    involved_in ecdysteroid metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9514-PA
    NP_572981.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14885952..14896891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132753.3 → NP_572981.1  uncharacterized protein Dmel_CG9514 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572981.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQN2, Q9VY06
      Related
      FBpp0073797
      Conserved Domains (3) summary
      PRK02106
      Location:95 → 679
      PRK02106; choline dehydrogenase; Validated
      pfam05199
      Location:505 → 648
      GMC_oxred_C; GMC oxidoreductase
      cl21454
      Location:167 → 391
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQN2 Q8MQN2
    Q9VY06 Q9VY06

    Gene LinkOut

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