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    CG18530 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 59241, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18530provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0042207
    Locus tag
    Dmel_CG18530
    See related
    AllianceGenome:FB:FBgn0042207
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12294; Dmel\CG18530
    Summary
    Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid metabolic process. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18530 in Genome Data Viewer
    Location:
    87C3-87C3; 3-52 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12633359..12634670)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8459081..8460374)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sorting nexin 3 Neighboring gene CCR4-NOT transcription complex subunit 10 Neighboring gene antisense RNA:CR46018 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dietary Curcumin Intake and Its Effects on the Transcriptome and Metabolome of Drosophila melanogaster. Belcher S, et al. Int J Mol Sci, 2024 Jun 14. PMID 38928266, Free PMC Article
    2. Dissection of Complex, Fitness-Related Traits in Multiple Drosophila Mapping Populations Offers Insight into the Genetic Control of Stress Resistance. Everman ER, et al. Genetics, 2019 Apr. PMID 30760490, Free PMC Article
    3. A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock. Moskalev A, et al. BMC Genomics, 2015. PMID 26694630, Free PMC Article
    4. Asymmetric sequence divergence of duplicate genes. Conant GC, et al. Genome Res, 2003 Sep. PMID 12952876, Free PMC Article
    5. Comparative and functional genomics of lipases in holometabolous insects. Horne I, et al. Insect Biochem Mol Biol, 2009 Aug. PMID 19540341

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables triacylglycerol lipase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18530-PA
    NP_652714.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12633359..12634670
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144457.3 → NP_652714.2  uncharacterized protein Dmel_CG18530 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652714.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W339, Q9VG50
      Related
      FBpp0082113
      Conserved Domains (2) summary
      PLN02872
      Location:22 → 377
      PLN02872; triacylglycerol lipase
      pfam04083
      Location:22 → 82
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VG50 Q9VG50

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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