CCHa1 CCHamide-1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CCHa1provided by FlyBase
Official Full Name: CCHamide-1provided by FlyBase
Primary source: FLYBASE:FBgn0038199
Locus tag: Dmel_CG14358
See related: AllianceGenome:FB:FBgn0038199
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CCH1; ccha1; CCha1; CCHA1; CCM; CG14358; Dm-CCHa1; Dmel\CG14358
Summary: Enables neuropeptide hormone activity. Involved in neuropeptide signaling pathway. Located in extracellular space. Is expressed in several structures, including DN1a neurons; adult optic lobe; enteroendocrine cell; gut section; and synaptic neuropil domain. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (14092504..14096835, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (9918226..9922557, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Pigment-dispersing factor and CCHamide1 in the Drosophila circadian clock network.
Title: Pigment-dispersing factor and CCHamide1 in the Drosophila circadian clock network.
orcokinin B, CCHamide 1, and CCHamide 2 expression in Drosophila is reported.
Title: More Drosophila enteroendocrine peptides: Orcokinin B and the CCHamides 1 and 2.
G-protein-coupled receptors coded for by genes CG14593 and CG30106 that are selectively activated by Drosophila CCH-amide-1 and CCH-amide-2, respectively, were cloned.
Title: The Drosophila genes CG14593 and CG30106 code for G-protein-coupled receptors specifically activated by the neuropeptides CCHamide-1 and CCHamide-2.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables neuropeptide hormone activity	IBA Inferred from Biological aspect of Ancestor more info
enables neuropeptide hormone activity	IDA Inferred from Direct Assay more info	PubMed
enables neuropeptide hormone activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuropeptide signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in neuropeptide signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular space	ISM Inferred from Sequence Model more info	PubMed