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    CG15803 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42206, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15803provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038606
    Locus tag
    Dmel_CG15803
    See related
    AllianceGenome:FB:FBgn0038606
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15803; lincRNA.804
    Summary
    Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human MPDZ (multiple PDZ domain crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15803 in Genome Data Viewer
    Location:
    91A2-91A3; 3-63 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18330932..18360728, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14156654..14186450, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Protein Kinase D Neighboring gene nazgul Neighboring gene long non-coding RNA:CR45634 Neighboring gene WRN exonuclease Neighboring gene hemingway

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A natural genetic variation screen identifies insulin signaling, neuronal communication, and innate immunity as modifiers of hyperglycemia in the absence of Sirt1. Palu RAS, et al. G3 (Bethesda), 2022 May 30. PMID 35435227, Free PMC Article
    2. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
    3. Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster. Dembeck LM, et al. PLoS Genet, 2015 May. PMID 25933381, Free PMC Article
    4. Hidden genetic variation shapes the structure of functional elements in Drosophila. Chakraborty M, et al. Nat Genet, 2018 Jan. PMID 29255259, Free PMC Article
    5. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c18333274-18331839 mobile_element_type = transposon:hopper{}1383
    • Loc: c18346729-18346692 mobile_element_type = transposon:INE-1{}4878

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15803-PB
    CG15803-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18330932..18360728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142456.4 → NP_650713.2  uncharacterized protein Dmel_CG15803, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650713.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE88
      Conserved Domains (2) summary
      smart00228
      Location:307 → 393
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:17 → 89
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

    2. NM_001300459.1 → NP_001287388.1  uncharacterized protein Dmel_CG15803, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287388.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LIC4
      Conserved Domains (2) summary
      smart00228
      Location:307 → 393
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:17 → 89
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LIC4 A0A0B4LIC4
    Q9VE88 Q9VE88

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