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    Jon65Aiii Jonah 65Aiii [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38683, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Jon65Aiiiprovided by FlyBase
    Official Full Name
    Jonah 65Aiiiprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035665
    Locus tag
    Dmel_CG6483
    See related
    AllianceGenome:FB:FBgn0035665
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:GressD16; anon-WO0140519.59; CG6483; Dmel\CG6483; Jon65; Jon65A; jon65Aiii; SP98
    Summary
    Enables serine hydrolase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. Is expressed in embryonic midgut chamber; embryonic/larval midgut; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Jon65Aiii in Genome Data Viewer
    Location:
    65A3-65A3; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6050757..6051690)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6043857..6044790)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Jonah 65Aiv Neighboring gene Jonah 65Aii Neighboring gene Jonah 65Ai

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues. Gress TM, et al. Mamm Genome, 1992. PMID 1450511
    2. Homeostasis of glutamate neurotransmission is altered in Drosophila Inositol 1,4,5-trisphosphate receptor mutants. Nair S, et al. Invert Neurosci, 2007 Sep. PMID 17492321
    3. Developmental and functional analysis of Jonah gene expression. Carlson JR, et al. Dev Biol, 1985 Apr. PMID 2416611
    4. Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila. González J, et al. PLoS Genet, 2010 Apr 8. PMID 20386746, Free PMC Article
    5. A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes. Bozler J, et al. PLoS Genet, 2017 Oct. PMID 29084214, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables serine hydrolase activity HDA PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    jonah 65Aiii
    Names
    CG6483-PA
    Jon65Aiii-PA
    jonah 65
    jonah 65A
    NP_648013.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6050757..6051690
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139756.3 → NP_648013.1  jonah 65Aiii [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648013.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRS7
      Related
      FBpp0076749
      Conserved Domains (2) summary
      smart00020
      Location:39 → 266
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:40 → 269
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRS7 Q9VRS7

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