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    CG7601 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43502, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7601provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027583
    Locus tag
    Dmel_CG7601
    See related
    AllianceGenome:FB:FBgn0027583
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH06026; DHRS7B; Dmel\CG7601
    Summary
    Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to be active in membrane. Is expressed in adult head. Orthologous to several human genes including DHRS7B (dehydrogenase/reductase 7B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7601 in Genome Data Viewer
    Location:
    99B9-99B9; 3-99 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29735269..29736745, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25560991..25562467, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pterin-4a-carbinolamine dehydratase Neighboring gene N(alpha)-acetyltransferase 40 Neighboring gene uncharacterized protein Neighboring gene Kuzbanian-like Neighboring gene Complex I intermediate-associated protein, 30 kDa Neighboring gene Glucosamine-phosphate N-acetyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of two pathways mediating protein targeting from ER to lipid droplets. Song J, et al. Nat Cell Biol, 2022 Sep. PMID 36050470, Free PMC Article
    2. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
    3. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article
    4. Systematic analysis of the Frazzled receptor interactome establishes previously unreported regulators of axon guidance. Zang Y, et al. Development, 2023 Aug 1. PMID 37526651, Free PMC Article
    5. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Jimenez-Sanchez M, et al. Nat Chem Biol, 2015 May. PMID 25848931, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables all-trans-retinol dehydrogenase (NAD+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7601-PA
    NP_651717.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29735269..29736745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143460.4 → NP_651717.1  uncharacterized protein Dmel_CG7601 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651717.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9Y140
      Related
      FBpp0084910
      Conserved Domains (2) summary
      cd05332
      Location:51 → 310
      11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
      PRK06181
      Location:53 → 314
      PRK06181; short chain dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y140.1 Q9Y140

    Gene LinkOut

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