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    CG11353 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38560, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11353provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035557
    Locus tag
    Dmel_CG11353
    See related
    AllianceGenome:FB:FBgn0035557
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.162; Dmel\CG11353
    Summary
    Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; embryonic proventriculus inner layer; embryonic ventral epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11353 in Genome Data Viewer
    Location:
    64B9-64B9; 3-12 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4533170..4539270)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4533170..4539270)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Neurotrophin 1 Neighboring gene Tie-like receptor tyrosine kinase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of the neurodegeneration gene drop-dead and characterization of additional phenotypes of its mutation. Blumenthal EM. Fly (Austin), 2008 Jul-Aug. PMID 18719404, Free PMC Article
    2. Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep. Harbison ST, et al. PLoS Genet, 2017 Dec. PMID 29240764, Free PMC Article
    3. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11353-PA
    CG11353-PB
    NP_647915.1
    NP_729013.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4533170..4539270
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139658.4 → NP_647915.1  uncharacterized protein Dmel_CG11353, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647915.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA7
      Related
      FBpp0073165
      Conserved Domains (3) summary
      smart00703
      Location:118 → 243
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:349 → 752
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
      pfam01757
      Location:352 → 729
      Acyl_transf_3; Acyltransferase family

    2. NM_168093.3 → NP_729013.1  uncharacterized protein Dmel_CG11353, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729013.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA7
      Related
      FBpp0073164
      Conserved Domains (3) summary
      smart00703
      Location:118 → 243
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:349 → 752
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
      pfam01757
      Location:352 → 729
      Acyl_transf_3; Acyltransferase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZA7 Q9VZA7

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