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    CG10375 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42812, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG10375provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039116
    Locus tag
    Dmel_CG10375
    See related
    AllianceGenome:FB:FBgn0039116
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10375
    Summary
    Predicted to be active in nucleus. Orthologous to human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10375 in Genome Data Viewer
    Location:
    95B1-95B1; 3-80 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23767712..23768984)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19593434..19594706)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene undicht Neighboring gene Lipid storage droplet-1 Neighboring gene uncharacterized protein Neighboring gene twister Neighboring gene uncharacterized protein Neighboring gene Nucleoporin 98-96kD

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington's disease related aggregates. Deo A, et al. Sci Rep, 2024 Sep 6. PMID 39242711, Free PMC Article
    2. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
    3. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article
    4. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article
    5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10375-PA
    CG10375-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23767712..23768984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142928.3 → NP_651185.1  uncharacterized protein Dmel_CG10375, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651185.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCH9
      Related
      FBpp0083849
      Conserved Domains (1) summary
      cd06257
      Location:54 → 109
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...

    2. NM_001170233.1 → NP_001163704.1  uncharacterized protein Dmel_CG10375, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163704.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AVU6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0AVU6 A0AVU6
    Q9VCH9 Q9VCH9

    Gene LinkOut

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