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    CG2991 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33488, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2991provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031474
    Locus tag
    Dmel_CG2991
    See related
    AllianceGenome:FB:FBgn0031474
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT10107; CT42388; Dmel\CG2991
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2991 in Genome Data Viewer
    Location:
    23B6-23B7; 2-7 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2857164..2868548)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2857164..2868548)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S21 Neighboring gene Interferon-related developmental regulator 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Peroxiredoxin 6a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription. Su R, et al. Nucleic Acids Res, 2024 Apr 24. PMID 38416578, Free PMC Article
    2. LRRK2(I2020T) functional genetic interactors that modify eye degeneration and dopaminergic cell loss in Drosophila. Marcogliese PC, et al. Hum Mol Genet, 2017 Apr 1. PMID 28158614, Free PMC Article
    3. Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep. Harbison ST, et al. PLoS Genet, 2017 Dec. PMID 29240764, Free PMC Article
    4. A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages. Corrales M, et al. Neural Dev, 2022 Aug 24. PMID 36002881, Free PMC Article
    5. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2991-PA
    CG2991-PB
    CG2991-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2857164..2868548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164509.3 → NP_722856.1  uncharacterized protein Dmel_CG2991, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722856.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQI2
      Related
      FBpp0077310
      Conserved Domains (2) summary
      COG5183
      Location:389 → 494
      SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]
      cd16495
      Location:392 → 443
      RING_CH-C4HC3_MARCH; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH proteins (MARCH)

    2. NM_134881.6 → NP_608725.1  uncharacterized protein Dmel_CG2991, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608725.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQI2
      Related
      FBpp0077311
      Conserved Domains (2) summary
      COG5183
      Location:389 → 494
      SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]
      cd16495
      Location:392 → 443
      RING_CH-C4HC3_MARCH; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH proteins (MARCH)

    3. NM_164510.3 → NP_722857.1  uncharacterized protein Dmel_CG2991, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722857.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQI2
      Related
      FBpp0077312
      Conserved Domains (2) summary
      COG5183
      Location:389 → 494
      SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]
      cd16495
      Location:392 → 443
      RING_CH-C4HC3_MARCH; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH proteins (MARCH)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQI2 Q9VQI2

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