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    CG12728 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31526, updated on 28-Oct-2024

    Summary

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    Official Symbol
    CG12728provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029825
    Locus tag
    Dmel_CG12728
    See related
    AllianceGenome:FB:FBgn0029825
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12728; XLF1; XRCC4
    Orthologs
    all
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    Genomic context

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    See CG12728 in Genome Data Viewer
    Location:
    5C10-5C10; 1-14 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5942606..5945250)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5836639..5839283)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44108 Neighboring gene Serine hydroxymethyl transferase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. REC drives recombination to repair double-strand breaks in animal mtDNA. Klucnika A, et al. J Cell Biol, 2023 Jan 2. PMID 36355348, Free PMC Article
    2. DNA Repair in Drosophila: Mutagens, Models, and Missing Genes. Sekelsky J. Genetics, 2017 Feb. PMID 28154196, Free PMC Article
    3. Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1. Barclay SS, et al. Hum Mol Genet, 2014 Mar 1. PMID 24179173
    4. Effect of Larval Nutrition on Maternal mRNA Contribution to the Drosophila Egg. Crofton AE, et al. G3 (Bethesda), 2018 May 31. PMID 29666195, Free PMC Article
    5. Copper homeostasis gene discovery in Drosophila melanogaster. Norgate M, et al. Biometals, 2007 Jun. PMID 17216353

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12728-PA
    CG12728-PB
    X-ray repair cross-complementing protein 4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5942606..5945250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297989.1 → NP_001284918.1  uncharacterized protein Dmel_CG12728, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W455
      Conserved Domains (2) summary
      pfam09184
      Location:268 → 403
      PPP4R2; PPP4R2
      pfam09302
      Location:39 → 150
      XLF; XLF-Cernunnos, XRcc4-like factor, NHEJ component

    2. NM_132052.4 → NP_572280.2  uncharacterized protein Dmel_CG12728, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572280.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W455
      Related
      FBpp0070824
      Conserved Domains (2) summary
      pfam09184
      Location:268 → 403
      PPP4R2; PPP4R2
      pfam09302
      Location:39 → 150
      XLF; XLF-Cernunnos, XRcc4-like factor, NHEJ component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W455 Q9W455

    Gene LinkOut

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