U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG1409 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31689, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG1409provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029964
    Locus tag
    Dmel_CG1409
    See related
    AllianceGenome:FB:FBgn0029964
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT29287; D.M.BLPp; Dmel\CG1409
    Summary
    Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in testis. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG1409 in Genome Data Viewer
    Location:
    7C1-7C1; 1-21 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7858173..7858794)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7752206..7752827)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Carbonic anhydrase-related protein A Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 7b Neighboring gene antisense RNA:CR43615 Neighboring gene defective chorion

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The black-pearl gene of Drosophila defines a novel conserved protein family and is required for larval growth and survival. Becker S, et al. Gene, 2001 Jan 10. PMID 11179663
    2. Readapting to DCV Infection without Wolbachia: Frequency Changes of Drosophila Antiviral Alleles Can Replace Endosymbiont Protection. Faria VG, et al. Genome Biol Evol, 2018 Jul 1. PMID 29947761, Free PMC Article
    3. Analysis of Drosophila melanogaster testis transcriptome. Vedelek V, et al. BMC Genomics, 2018 Sep 24. PMID 30249207, Free PMC Article
    4. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article
    5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TIM23 mitochondrial import inner membrane translocase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG1409-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7858173..7858794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132181.2 → NP_572409.2  uncharacterized protein Dmel_CG1409 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572409.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DMN1, Q9W3P5
      Conserved Domains (1) summary
      cl02542
      Location:1 → 113
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZ64 Q8MZ64
    Q9W3P5 Q9W3P5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools