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    nw narrow [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772015, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nwprovided by FlyBase
    Official Full Name
    narrowprovided by FlyBase
    Primary source
    FLYBASE:FBgn0283508
    Locus tag
    Dmel_CG43164
    See related
    AllianceGenome:FB:FBgn0283508
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe2D7; anon2D7; Bla; CG18431; CG33006; CG43164; CG4844; CG4844a; CG4844b; Dmel\CG43164; lance
    Old locus tag
    Dmel_CG18431; Dmel_CG4844
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Involved in regulation of imaginal disc-derived wing size. Located in extracellular space. Is expressed in several structures, including clypeo-labral primordium; embryonic head epidermis; epidermis; gut section; and sense organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    Location:
    54B18-54C1; 2-82 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17502354..17508645)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13389859..13396150)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ecto-5'-nucleotidase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cathepsin K2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crossover Modifiers in the Third Chromosome of DROSOPHILA MELANOGASTER. Payne F. Genetics, 1924 Jul. PMID 17246043, Free PMC Article
    2. A narrow gene encoding an extracellular matrix is involved in the formation of the footpad hairs in Drosophila melanogaster. Tanaka K, et al. MicroPubl Biol, 2023. PMID 37090156, Free PMC Article
    3. Enhanced flight performance by genetic manipulation of wing shape in Drosophila. Ray RP, et al. Nat Commun, 2016 Mar 1. PMID 26926954, Free PMC Article
    4. The mus206 gene of Drosophila melanogaster is required in the excision repair of alkylation-induced DNA lesions. Huang W, et al. Mutat Res, 1997 Aug. PMID 9298117
    5. Oogenesis in adult Drosophila melanogaster. IV. Hereditary ovarian tumors. KING RC, et al. Growth, 1957 Dec. PMID 13512753

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of imaginal disc-derived wing size IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    narrow
    Names
    CG43164-PA
    CG43164-PB
    CG43164-PC
    CG43164-PD
    CG43164-PE
    anon-fast-evolving-2D7
    blade
    nw-PA
    nw-PB
    nw-PC
    nw-PD
    nw-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17502354..17508645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032264.4 → NP_001027435.2  narrow, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027435.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C3KGN2
      Conserved Domains (1) summary
      cd00037
      Location:31 → 176
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    2. NM_001032266.4 → NP_001027437.1  narrow, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027437.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAU2
      Conserved Domains (1) summary
      cd00037
      Location:42 → 176
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    3. NM_001202034.3 → NP_001188963.1  narrow, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188963.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JCT4
      Conserved Domains (1) summary
      cd00037
      Location:42 → 175
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    4. NM_001032265.4 → NP_001027436.2  narrow, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027436.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAU3
      Conserved Domains (1) summary
      cd00037
      Location:31 → 175
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    5. NM_001259468.2 → NP_001246397.1  narrow, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246397.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAU2
      Conserved Domains (1) summary
      cd00037
      Location:42 → 176
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JCT4 A0A0B4JCT4
    A1ZAU2 A1ZAU2
    A1ZAU3 A1ZAU3
    C3KGN2 C3KGN2
    O16054 O16054
    Q7K140 Q7K140

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