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    CG10543 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37379, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10543provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034570
    Locus tag
    Dmel_CG10543
    See related
    AllianceGenome:FB:FBgn0034570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10543
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Involved in gravitaxis. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10543 in Genome Data Viewer
    Location:
    57B5-57B5; 2-92 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20996220..21007740)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16883725..16895245)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene dim gamma-tubulin 3 Neighboring gene Proteasome alpha3 subunit Neighboring gene uncharacterized protein Neighboring gene grauzone

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gravitaxis in Drosophila melanogaster: a forward genetic screen. Armstrong JD, et al. Genes Brain Behav, 2006 Apr. PMID 16594976
    2. Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. Herranz R, et al. Mol Ecol, 2010 Oct. PMID 20819157
    3. Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland. Tokusumi Y, et al. PLoS One, 2012. PMID 22911822, Free PMC Article
    4. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973
    5. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in gravitaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10543-PA
    CG10543-PD
    CG10543-PE
    CG10543-PF
    CG10543-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20996220..21007740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274183.1 → NP_001261112.1  uncharacterized protein Dmel_CG10543, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFE1
      Conserved Domains (2) summary
      PHA00733
      Location:804 → 860
      PHA00733; hypothetical protein
      sd00017
      Location:868 → 888
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_001382009.1 → NP_001369100.1  uncharacterized protein Dmel_CG10543, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6M3Q7L9
      Conserved Domains (2) summary
      PHA00733
      Location:804 → 860
      PHA00733; hypothetical protein
      sd00017
      Location:868 → 888
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_137690.4 → NP_611534.2  uncharacterized protein Dmel_CG10543, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611534.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLW9, Q9W2N8
      Related
      FBpp0071453
      Conserved Domains (2) summary
      PHA00733
      Location:804 → 860
      PHA00733; hypothetical protein
      sd00017
      Location:868 → 888
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. NM_166416.2 → NP_726015.2  uncharacterized protein Dmel_CG10543, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726015.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLW9, Q9W2N8
      Conserved Domains (2) summary
      PHA00733
      Location:804 → 860
      PHA00733; hypothetical protein
      sd00017
      Location:868 → 888
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. NM_176241.3 → NP_788421.2  uncharacterized protein Dmel_CG10543, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788421.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86BG2
      Conserved Domains (2) summary
      PHA00733
      Location:801 → 857
      PHA00733; hypothetical protein
      sd00017
      Location:865 → 885
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFE1 A0A0B4KFE1
    A0A6M3Q7L9 A0A6M3Q7L9
    Q86BG2 Q86BG2
    Q8MSN5 Q8MSN5
    Q9W2N8 Q9W2N8

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