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    CG11396 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40296, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11396provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037022
    Locus tag
    Dmel_CG11396
    See related
    AllianceGenome:FB:FBgn0037022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11396; TRAPPC12
    Summary
    Predicted to be involved in Golgi vesicle transport. Located in Golgi apparatus. Part of TRAPPIII protein complex. Is expressed in adult head and organism. Orthologous to human TRAPPC12 (trafficking protein particle complex subunit 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11396 in Genome Data Viewer
    Location:
    77E6-77E6; 3-47 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20786340..20788137, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20779440..20781237, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pitslre Neighboring gene Peroxin 16 Neighboring gene Peroxin 14 Neighboring gene Phosphorylated CTD-interacting factor 1 Neighboring gene antisense RNA:CR46484 Neighboring gene Six4 Neighboring gene long non-coding RNA:CR43705

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1. Galindo A, et al. EMBO J, 2021 Jun 15. PMID 34018214, Free PMC Article
    2. PINK1 and Parkin regulate IP(3)R-mediated ER calcium release. Ham SJ, et al. Nat Commun, 2023 Aug 25. PMID 37626046, Free PMC Article
    3. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. Riedel F, et al. J Cell Biol, 2018 Feb 5. PMID 29273580, Free PMC Article
    4. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of TRAPP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TRAPPIII protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11396-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20786340..20788137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140998.3 → NP_649255.1  uncharacterized protein Dmel_CG11396 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649255.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPB6
      Related
      FBpp0077934
      Conserved Domains (3) summary
      sd00006
      Location:367 → 392
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:400 → 430
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:367 → 429
      TPR_11; TPR repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPB6 Q9VPB6

    Gene LinkOut

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