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    CG4829 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4829provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030796
    Locus tag
    Dmel_CG4829
    See related
    AllianceGenome:FB:FBgn0030796
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4829
    Summary
    Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be active in plasma membrane. Is expressed in several structures, including CNS glial cell; adult brain cell body rind; adult head; synaptic neuropil domain; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1) and GGT2P (gamma-glutamyltransferase 2, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4829 in Genome Data Viewer
    Location:
    15A10-15A11; 1-55 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16811699..16826494)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16705732..16720527)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44053 Neighboring gene uncharacterized protein Neighboring gene pickpocket 28 Neighboring gene long non-coding RNA:CR44129 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Regulator of G-protein signaling 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of an RNA regulatory map between Drosophila and mammals. Brooks AN, et al. Genome Res, 2011 Feb. PMID 20921232, Free PMC Article
    2. Proteomic identification of Drosophila melanogaster male accessory gland proteins, including a pro-cathepsin and a soluble gamma-glutamyl transpeptidase. Walker MJ, et al. Proteome Sci, 2006 May 2. PMID 16670001, Free PMC Article
    3. Systematic determination of patterns of gene expression during Drosophila embryogenesis. Tomancak P, et al. Genome Biol, 2002. PMID 12537577, Free PMC Article
    4. Sex-Specific Transcript Diversity in the Fly Head Is Established during Pupal Stages and Adulthood and Is Largely Independent of the Mating Process and the Germline. Mohr C, et al. Sex Dev, 2017. PMID 28273663
    5. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glutathione hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutathione catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutathione catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4829-PA
    CG4829-PB
    CG4829-PC
    CG4829-PD
    CG4829-PE
    CG4829-PF
    NP_001097004.1
    NP_001097005.1
    NP_001259628.1
    NP_573170.2
    NP_728029.1
    NP_728030.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16811699..16826494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167550.2 → NP_728030.2  uncharacterized protein Dmel_CG4829, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728030.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B8A431, Q7KUX2
      Related
      FBpp0074110
      Conserved Domains (1) summary
      pfam01019
      Location:306 → 817
      G_glu_transpept; Gamma-glutamyltranspeptidase

    2. NM_001103535.2 → NP_001097005.1  uncharacterized protein Dmel_CG4829, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097005.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV19, E8NH33
      Conserved Domains (1) summary
      pfam01019
      Location:216 → 727
      G_glu_transpept; Gamma-glutamyltranspeptidase

    3. NM_001272699.1 → NP_001259628.1  uncharacterized protein Dmel_CG4829, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259628.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PHT3, Q8T0R6
      Conserved Domains (1) summary
      pfam01019
      Location:1 → 486
      G_glu_transpept; Gamma-glutamyltranspeptidase

    4. NM_167549.2 → NP_728029.1  uncharacterized protein Dmel_CG4829, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728029.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH33, Q9VXA5
      Related
      FBpp0074111
      Conserved Domains (1) summary
      pfam01019
      Location:261 → 772
      G_glu_transpept; Gamma-glutamyltranspeptidase

    5. NM_001103534.2 → NP_001097004.1  uncharacterized protein Dmel_CG4829, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097004.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JV25, E8NH33
      Conserved Domains (1) summary
      pfam01019
      Location:171 → 682
      G_glu_transpept; Gamma-glutamyltranspeptidase

    6. NM_132942.3 → NP_573170.2  uncharacterized protein Dmel_CG4829, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573170.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH33, Q9VXA5
      Related
      FBpp0074112
      Conserved Domains (1) summary
      pfam01019
      Location:261 → 772
      G_glu_transpept; Gamma-glutamyltranspeptidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JV19 A8JV19
    A8JV25 A8JV25
    M9PHT3 M9PHT3
    Q7KUX2 Q7KUX2
    Q8T0R6 Q8T0R6
    Q9VXA5 Q9VXA5

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