U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG14718 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41413, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG14718provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037939
    Locus tag
    Dmel_CG14718
    See related
    AllianceGenome:FB:FBgn0037939
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg14718; Dmel\CG14718
    Summary
    Predicted to enable mRNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in connective tissue cancer (multiple); essential tremor 4; and neurodegenerative disease (multiple). Orthologous to human FUS (FUS RNA binding protein) and TAF15 (TATA-box binding protein associated factor 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG14718 in Genome Data Viewer
    Location:
    86E16-86E16; 3-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11700614..11702720)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7526336..7528442)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene 48 related 3 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46011 Neighboring gene inhibitor-t

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ephemeral association between gene CG5762 and hybrid male sterility in Drosophila sibling species. Ma D, et al. J Mol Evol, 2011 Oct. PMID 22052252
    2. Scrutinizing the human TEX genes in the context of human male infertility. Sieper MH, et al. Andrology, 2024 Mar. PMID 37594251
    3. Requirement of Split ends for epigenetic regulation of Notch signal-dependent genes during infection-induced hemocyte differentiation. Jin LH, et al. Mol Cell Biol, 2009 Mar. PMID 19139277, Free PMC Article
    4. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article
    5. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG14718-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11700614..11702720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141850.2 → NP_650107.1  uncharacterized protein Dmel_CG14718 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650107.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961N8, Q9VGJ3
      Related
      FBpp0081902, FBtr0082426
      Conserved Domains (5) summary
      COG0724
      Location:222 → 335
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      sd00025
      Location:343 → 362
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:343 → 366
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl02656
      Location:397 → 423
      zf-RanBP; Zn-finger in Ran binding protein and others
      cl17169
      Location:223 → 302
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGJ3 Q9VGJ3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous