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    Dnz1 DNZDHHC/NEW1 zinc finger protein 11 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34503, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dnz1provided by FlyBase
    Official Full Name
    DNZDHHC/NEW1 zinc finger protein 11provided by FlyBase
    Primary source
    FLYBASE:FBgn0027453
    Locus tag
    Dmel_CG6627
    See related
    AllianceGenome:FB:FBgn0027453
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6627; Dmel\CG6627; DNZ1
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Located in endoplasmic reticulum. Is expressed in several structures, including adult head; anterior endoderm; brain; central nervous system; and embryonic/larval midgut primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Dnz1 in Genome Data Viewer
    Location:
    32B1-32B2; 2-43 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10854435..10856644, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10854435..10856644, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Porin2 Neighboring gene porin Neighboring gene SET and MYND domain containing, arthropod-specific, member 3 Neighboring gene aurora B Neighboring gene Signal transducing adaptor molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic mosaic analysis with a repressible cell marker screen to identify genes involved in tracheal cell migration during Drosophila air sac morphogenesis. Chanut-Delalande H, et al. Genetics, 2007 Aug. PMID 17603108, Free PMC Article
    2. The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes. Porcellato E, et al. PLoS One, 2022. PMID 35960718, Free PMC Article
    3. The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial. Mesilaty-Gross S, et al. Gene, 1999 Apr 29. PMID 10231582
    4. Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense. Deng Z, et al. J Genet Genomics, 2023 Dec. PMID 37343788
    5. The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Bannan BA, et al. Fly (Austin), 2008 Jul-Aug. PMID 18719403, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNZDHHC/NEW1 zinc finger protein 11
    Names
    CG6627-PA
    DNZDHHC/NEW1 zinc-finger protein 11
    Dnz1-PA
    NP_477449.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10854435..10856644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058101.4 → NP_477449.1  DNZDHHC/NEW1 zinc finger protein 11 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477449.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKN8
      Related
      FBpp0079770
      Conserved Domains (1) summary
      pfam01529
      Location:97 → 228
      DHHC; DHHC palmitoyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKN8 Q9VKN8
    Q9XTL3 Q9XTL3

    Gene LinkOut

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