scat scattered [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: scatprovided by FlyBase
Official Full Name: scatteredprovided by FlyBase
Primary source: FLYBASE:FBgn0011232
Locus tag: Dmel_CG3766
See related: AllianceGenome:FB:FBgn0011232
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG3766; Dmel\CG3766; ms(2)05289; ms(2)30B; Scat; Vps54
Summary: Predicted to enable syntaxin binding activity. Involved in endocytic recycling and spermatid development. Located in Golgi trans cisterna. Part of GARP complex. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gland; gut section; and mesoderm. Used to study motor neuron disease. Orthologous to human VPS54 (VPS54 subunit of GARP complex). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (9431405..9435341)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (9431405..9435341)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density.
Title: Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables syntaxin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in Golgi to vacuole transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi to vacuole transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in acrosome assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in endocytic recycling	IDA Inferred from Direct Assay more info	PubMed
involved_in retrograde transport, endosome to Golgi	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde transport, endosome to Golgi	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, endosome to Golgi	ISS Inferred from Sequence or Structural Similarity more info
involved_in sperm individualization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermatid nucleus elongation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of GARP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GARP complex	IDA Inferred from Direct Assay more info	PubMed
part_of GARP complex	IEA Inferred from Electronic Annotation more info
part_of GARP complex	ISS Inferred from Sequence or Structural Similarity more info
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in Golgi trans cisterna	IDA Inferred from Direct Assay more info	PubMed

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