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    rpoC DNA-directed RNA polymerase subunit beta' [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888177, updated on 27-Nov-2023

    Summary

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    Gene symbol
    rpoC
    Gene description
    DNA-directed RNA polymerase subunit beta'
    Locus tag
    Rv0668
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (763370..767320)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene ribonuclease VapC8 Neighboring gene membrane protein Neighboring gene DNA-directed RNA polymerase subunit beta Neighboring gene neutral ceramidase Neighboring gene endonuclease IV

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis. Wang S, et al. Front Med, 2020 Feb. PMID 31938981
    2. Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission. de Vos M, et al. Antimicrob Agents Chemother, 2013 Feb. PMID 23208709, Free PMC Article
    3. Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru. Vargas AP, et al. Int J Mycobacteriol, 2020 Apr-Jun. PMID 32474533, Free PMC Article
    4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru.
      Title: Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru.
    2. Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis.
      Title: Characteristics of compensatory mutations in the rpoC gene and their association with compensated transmission of Mycobacterium tuberculosis.
    3. a role for rpoC mutations in the transmission of multidrug-resistant tuberculosis
      Title: Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase subunit beta'
    NP_215182.1
    • RpoC (transcriptase beta' chain) (RNA polymerase beta' subunit)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      763370..767320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215182.1 DNA-directed RNA polymerase subunit beta' [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215182.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      R4LZQ5
      Conserved Domains (1) summary
      PRK00566
      Location:3 → 1282
      PRK00566; DNA-directed RNA polymerase subunit beta'; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    5UH5_D.1
    5UH6_D.1
    5UH8_D.1
    5UH9_D.1
    5UHA_D.1
    5UHB_D.1
    5UHC_D.1
    5UHD_D.1
    5UHE_D.1
    5UHF_D.1
    5UHG_D.1
    6DV9_D.1
    6DVB_D.1
    6DVC_D.1
    6DVD_D.1
    6DVE_D.1
    6FBV_D.1
    P9WGY7.1

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