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    pks4 polyketide beta-ketoacyl synthase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886081, updated on 11-Dec-2020

    Summary

    Gene symbol
    pks4
    Gene description
    polyketide beta-ketoacyl synthase
    Locus tag
    Rv1181
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

    Sequence:
    NC_000962.3 (1315234..1319982)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene polyketide beta-ketoacyl synthase Neighboring gene acyltransferase papA3 Neighboring gene transmembrane transport protein MmpL10

    Pathways from PubChem

    General protein information

    Preferred Names
    polyketide beta-ketoacyl synthase
    NP_215697.1
    • Rv1180/Rv1181 fusion has been called msl3. The two CDS's may represent separate modules of the polyketide synthase.

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      1315234..1319982
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215697.1 polyketide beta-ketoacyl synthase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215697.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A089QRB9
      Conserved Domains (4) summary
      smart00823
      Location:14961574
      PKS_PP; Phosphopantetheine attachment site
      smart00829
      Location:9281218
      PKS_ER; Enoylreductase
      COG3321
      Location:3560
      PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
      cl25409
      Location:12621460
      SDR; Short-chain dehydrogenases/reductases (SDR)