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    acpM meromycolate extension acyl carrier protein [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888272, updated on 11-Dec-2020

    Summary

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    Gene symbol
    acpM
    Gene description
    meromycolate extension acyl carrier protein
    Locus tag
    Rv2244
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2517771..2518118)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene malonyl CoA-acyl carrier protein transacylase Neighboring gene ncRNA Neighboring gene 3-oxoacyl-ACP synthase 1 Neighboring gene 3-oxoacyl-ACP synthase 2 Neighboring gene acetyl-/propionyl-CoA carboxylase subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis. Biswas R, et al. FEBS Lett, 2019 Mar. PMID 30847903
    2. Mycobacterium tuberculosis acyl carrier protein inhibits macrophage apoptotic death by modulating the reactive oxygen species/c-Jun N-terminal kinase pathway. Paik S, et al. Microbes Infect, 2019 Jan-Feb. PMID 29981934
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis has been reported.
      Title: Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis.
    2. Overexpressing mycobacterial acyl carrier protein (AcpM) in Mycobacterium smegmatis (M. smegmatis) enhances intracellular survival in primary bone marrow-derived macrophages (BMDMs). AcpM overexpression decreases reactive oxygen species (ROS) generation and activation of c-Jun N-terminal kinase (JNK) signaling. Treatment of BMDMs with recombinant AcpM inhibits the apoptosis and ROS/JNK signaling induced by M. smegmatis.
      Title: Mycobacterium tuberculosis acyl carrier protein inhibits macrophage apoptotic death by modulating the reactive oxygen species/c-Jun N-terminal kinase pathway.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    meromycolate extension acyl carrier protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2517771..2518118
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_216760.1 meromycolate extension acyl carrier protein [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_216760.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P9WQF3
      UniProtKB/TrEMBL
      I6X3P5
      Conserved Domains (1) summary
      PRK00982
      Location:19 → 79
      acpP; acyl carrier protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WQF3.1

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