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    mbtB phenyloxazoline synthase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 885838, updated on 12-Feb-2021

    Summary

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    Gene symbol
    mbtB
    Gene description
    phenyloxazoline synthase
    Locus tag
    Rv2383c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2671593..2675837, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene peptide synthetase Neighboring gene peptide synthetase Neighboring gene polyketide synthetase Neighboring gene polyketide synthetase Neighboring gene 2,3-dihydroxybenzoate-AMP ligase Neighboring gene acetyl hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis. McMahon MD, et al. J Bacteriol, 2012 Jun. PMID 22447909, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The A domain of MbtB preferentially activates l-threonine.
      Title: Analyses of MbtB, MbtE, and MbtF suggest revisions to the mycobactin biosynthesis pathway in Mycobacterium tuberculosis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    phenyloxazoline synthase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2671593..2675837 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_216899.1 phenyloxazoline synthase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_216899.1

      Status: PROVISIONAL

      Conserved Domains (5) summary
      COG3208
      Location:1183 → 1413
      GrsT; Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism]
      COG3433
      Location:9 → 77
      DhbB2; Aryl carrier domain [Secondary metabolites biosynthesis, transport and catabolism]
      cd12114
      Location:566 → 1037
      A_NRPS_TlmIV_like; The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes
      cd19535
      Location:99 → 520
      Cyc_NRPS; Cyc (heterocyclization) domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family
      pfam00550
      Location:1064 → 1126
      PP-binding; Phosphopantetheine attachment site
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WQ63.1

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