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    leuD 3-isopropylmalate dehydratase small subunit [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888225, updated on 6-Oct-2023

    Summary

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    Gene symbol
    leuD
    Gene description
    3-isopropylmalate dehydratase small subunit
    Locus tag
    Rv2987c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (3344033..3344629, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene 8-oxo-dGTP diphosphatase Neighboring gene DNA-binding protein HU Neighboring gene 3-isopropylmalate dehydratase large subunit Neighboring gene transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the small subunit of isopropylmalate isomerase (Rv2987c) from Mycobacterium tuberculosis. Karuppasamy M, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009 Feb 1. PMID 19194004, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two carboxyl-terminally truncated variants of the small subunit of isopropylmalate isomerase have been designed, purified, and crystallized; two peaks indicate the presence of a a noncrystallographic twofold symmetry axis.
      Title: Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the small subunit of isopropylmalate isomerase (Rv2987c) from Mycobacterium tuberculosis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    3-isopropylmalate dehydratase small subunit
    NP_217503.1
    • isopropylmalate isomerase (alpha-IPM isomerase) (IPMI)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      3344033..3344629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_217503.1 3-isopropylmalate dehydratase small subunit [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_217503.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      R4M604
      Conserved Domains (1) summary
      PRK01641
      Location:1 → 194
      leuD; 3-isopropylmalate dehydratase small subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WK95.1

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