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    Rv1205 hypothetical protein [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886075, updated on 6-Jun-2024

    Summary

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    Gene symbol
    Rv1205
    Gene description
    hypothetical protein
    Locus tag
    Rv1205
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (1348719..1349282)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene succinyl-diaminopimelate desuccinylase DapE Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene fatty-acid--CoA ligase FadD6 Neighboring gene dihydropteroate synthase Neighboring gene glucosyl-3-phosphoglycerate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of the cytokinin-producing enzyme "lonely guy" (LOG) from Mycobacterium tuberculosis. Shang L, et al. Biochem Biophys Res Commun, 2022 Apr 2. PMID 35158209
    2. Cytokinin Signaling in Mycobacterium tuberculosis. Samanovic MI, et al. mBio, 2018 Jun 19. PMID 29921668, Free PMC Article
    3. Proteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxide. Samanovic MI, et al. Mol Cell, 2015 Mar 19. PMID 25728768, Free PMC Article
    4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Crystal structure of the cytokinin-producing enzyme ""lonely guy"" (LOG) from Mycobacterium tuberculosis.
      Title: Crystal structure of the cytokinin-producing enzyme "lonely guy" (LOG) from Mycobacterium tuberculosis.
    2. Cytokinins induces the expression of the Mycobacterium tuberculosis gene Rv0077c, which results in a loss of acid-fast staining of M. tuberculosis and altered metabolome. Rv0077c-induced loss of acid-fastness does not affect antibiotic susceptibility or attenuate bacterial growth in mice, consistent with an unaltered mycolic acid profile of Rv0077c-expressing cells.
      Title: Cytokinin Signaling in Mycobacterium tuberculosis.
    3. Accumulation of Rv1205 sensitizes M. tuberculosis to nitric oxide.Rv1205 is a phosphoribohydrolase that produces cytokinins.
      Title: Proteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxide.
    4. Rv1205 is a phosphoribohydrolase that catalyzes the final step in the production of bioactive cytokinins in Mycobacterium tuberculosis
      Title: Proteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxide.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hypothetical protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      1348719..1349282
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215721.1 hypothetical protein Rv1205 [Mycobacterium tuberculosis H37Rv]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A655ESW5
      Conserved Domains (1) summary
      TIGR00730
      Location:11 → 187
      TIGR00730; TIGR00730 family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O05306.1

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