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    eccA1 ESX-1 secretion system protein EccA1 [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886199, updated on 6-Jun-2024

    Summary

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    Gene symbol
    eccA1
    Gene description
    ESX-1 secretion system protein EccA1
    Locus tag
    Rv3868
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (4343314..4345035)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene ESX-1 secretion-associated protein EspF Neighboring gene ESX-1 secretion-associated protein EspG Neighboring gene ESX-1 secretion-associated protein EspH Neighboring gene ESX-1 secretion system protein EccB Neighboring gene ESX-1 secretion system protein EccCa

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria. Champion PA, et al. Mol Microbiol, 2009 Sep. PMID 19682254, Free PMC Article
    2. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. McLaughlin B, et al. PLoS Pathog, 2007 Aug 3. PMID 17676952, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The authors show that the EspC substrate interacts with Rv3868, a cytosolic AAA ATPase, through its C-terminus.
      Title: ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    ESX-1 secretion system protein EccA1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      4343314..4345035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_218385.1 ESX-1 secretion system protein EccA1 [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_218385.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      R4M3W5
      Conserved Domains (1) summary
      TIGR03922
      Location:27 → 566
      T7SS_EccA; type VII secretion AAA-ATPase EccA
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WPH9.1

    Gene LinkOut

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