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    Fbxo39 F-box protein 39 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303287, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fbxo39provided by RGD
    Official Full Name
    F-box protein 39provided by RGD
    Primary source
    RGD:1311464
    See related
    EnsemblRapid:ENSRNOG00000014953 AllianceGenome:RGD:1311464
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO39 (F-box protein 39). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 291.9) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fbxo39 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (57428259..57433468)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (56929699..56934911)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (58874028..58878445)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 17 open reading frame 100 Neighboring gene solute carrier family 13 member 5 Neighboring gene uncharacterized LOC134480819 Neighboring gene probable serine/threonine-protein kinase drkD-like Neighboring gene XIAP associated factor 1 Neighboring gene tektin 1 Neighboring gene uncharacterized LOC134480820 Neighboring gene smoothelin-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 39

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039018.1 → NP_001034107.1  F-box only protein 39

      See identical proteins and their annotated locations for NP_001034107.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100079
      UniProtKB/Swiss-Prot
      Q498T6, Q66H10
      UniProtKB/TrEMBL
      A6HGE9
      Related
      ENSRNOP00000020071.3, ENSRNOT00000020071.6
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      57428259..57433468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085999.2 → XP_038941927.1  F-box only protein 39 isoform X1

      UniProtKB/Swiss-Prot
      Q498T6, Q66H10
      UniProtKB/TrEMBL
      A6HGE9
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like

    2. XM_006246729.5 → XP_006246791.1  F-box only protein 39 isoform X1

      See identical proteins and their annotated locations for XP_006246791.1

      UniProtKB/Swiss-Prot
      Q498T6, Q66H10
      UniProtKB/TrEMBL
      A6HGE9
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like

    3. XM_006246727.5 → XP_006246789.1  F-box only protein 39 isoform X1

      See identical proteins and their annotated locations for XP_006246789.1

      UniProtKB/Swiss-Prot
      Q498T6, Q66H10
      UniProtKB/TrEMBL
      A6HGE9
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H10.2 GenPept UniProtKB/Swiss-Prot:Q66H10

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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