Gbs-70E Glycogen binding subunit 70E [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gbs-70Eprovided by FlyBase
Official Full Name: Glycogen binding subunit 70Eprovided by FlyBase
Primary source: FLYBASE:FBgn0036428
Locus tag: Dmel_CG9238
See related: AllianceGenome:FB:FBgn0036428
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.400; CG9238; Dmel\CG9238; GBS-70E
Summary: Enables glycogen binding activity and protein phosphatase 1 binding activity. Involved in behavioral response to ethanol and regulation of glycogen metabolic process. Part of protein phosphatase type 1 complex. Is expressed in several structures, including anlage in statu nascendi; embryonic/larval midgut primordium; endoderm anlage; gut section; and head epidermis primordium. Used to study alcohol use disorder. Orthologous to human PPP1R3B (protein phosphatase 1 regulatory subunit 3B) and PPP1R3C (protein phosphatase 1 regulatory subunit 3C). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (14540937..14550975, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (14534037..14544075, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Gbs-70E(CG9238) functions as the glycogen binding subunit of protein phosphatase 1.
Title: Functional analysis of the glycogen binding subunit CG9238/Gbs-70E of protein phosphatase 1 in Drosophila melanogaster.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables glycogen binding	IBA Inferred from Biological aspect of Ancestor more info
enables glycogen binding	IDA Inferred from Direct Assay more info	PubMed
enables protein phosphatase 1 binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase 1 binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in behavioral response to ethanol	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of glycogen catabolic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of glycogen biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of glycogen biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of glycogen metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of protein phosphatase type 1 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein phosphatase type 1 complex	IDA Inferred from Direct Assay more info	PubMed

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