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    RnpS1 RNA-binding protein S1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41147, updated on 27-Dec-2024

    Summary

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    Official Symbol
    RnpS1provided by FlyBase
    Official Full Name
    RNA-binding protein S1provided by FlyBase
    Primary source
    FLYBASE:FBgn0037707
    Locus tag
    Dmel_CG16788
    See related
    AllianceGenome:FB:FBgn0037707
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg16788; CG16788; DEK; Dmel\CG16788; rnps1; Rnps1; RNPS1
    Summary
    Predicted to enable mRNA binding activity. Involved in RNA splicing. Located in nucleoplasm. Is expressed in several structures, including adult brain cell body rind; brain; embryonic/larval midgut primordium; head epidermis primordium; and larval muscle cell. Orthologous to human RNPS1 (RNA binding protein with serine rich domain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RnpS1 in Genome Data Viewer
    Location:
    85D24-85D24; 3-48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9552034..9553747)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5377756..5379469)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene blistery Neighboring gene murashka Neighboring gene long non-coding RNA:CR42549 Neighboring gene uncharacterized protein Neighboring gene Branched chain keto acid dehydrogenase E1 subunit alpha Neighboring gene Adaptor Protein complex 1, mu subunit Neighboring gene Methyl-CpG binding domain protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A paired-end sequencing strategy to map the complex landscape of transcription initiation. Ni T, et al. Nat Methods, 2010 Jul. PMID 20495556, Free PMC Article
    2. The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Malone CD, et al. Genes Dev, 2014 Aug 15. PMID 25104425, Free PMC Article
    3. Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila. Dennis C, et al. Nat Commun, 2016 Dec 8. PMID 27929060, Free PMC Article
    4. The Interplay of Temperature and Genotype on Patterns of Alternative Splicing in Drosophila melanogaster. Jakšić AM, et al. Genetics, 2016 Sep. PMID 27440867, Free PMC Article
    5. REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. Gatfield D, et al. J Cell Biol, 2002 Nov 25. PMID 12438415, Free PMC Article

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ASAP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm HDA PubMed 
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein S1
    Names
    CG16788-PA
    RRM-domain protein
    RnpS1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9552034..9553747
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141646.2 → NP_649903.1  RNA-binding protein S1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649903.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHC0
      Related
      FBpp0081544
      Conserved Domains (2) summary
      COG0724
      Location:196 → 301
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12365
      Location:221 → 294
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHC0 Q9VHC0

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