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    CG12128 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36042, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12128provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033473
    Locus tag
    Dmel_CG12128
    See related
    AllianceGenome:FB:FBgn0033473
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12128
    Summary
    Predicted to enable RNA methyltransferase activity. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human SPOUT1 (SPOUT domain containing methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12128 in Genome Data Viewer
    Location:
    46D4-46D6; 2-61 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10026839..10030668)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5914344..5918173)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Protein kinase, cAMP-dependent, regulatory subunit type 2 Neighboring gene mir-4967 stem loop Neighboring gene long non-coding RNA:CR44294 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene oysgedart Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster. Szlanka T, et al. G3 (Bethesda), 2024 Sep 4. PMID 38985658, Free PMC Article
    2. Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells. Eliazer S, et al. PLoS Genet, 2014 Mar. PMID 24625679, Free PMC Article
    3. MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila. Daneshvar K, et al. Biol Open, 2013 Jan 15. PMID 23336071, Free PMC Article
    4. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Friedman AA, et al. Sci Signal, 2011 Oct 25. PMID 22028469, Free PMC Article
    5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA methyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12128-PA
    CG12128-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10026839..10030668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206068.2 → NP_995790.1  uncharacterized protein Dmel_CG12128, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995790.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z831, Q8MYV2
      Conserved Domains (1) summary
      cl12077
      Location:6 → 126
      Methyltrn_RNA_3; Putative RNA methyltransferase

    2. NM_136699.4 → NP_610543.1  uncharacterized protein Dmel_CG12128, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610543.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z830, Q8MSZ6
      Related
      FBpp0087481
      Conserved Domains (1) summary
      pfam02598
      Location:74 → 361
      Methyltrn_RNA_3; Putative RNA methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z830 A1Z830
    A1Z831 A1Z831
    Q8MSZ6 Q8MSZ6
    Q8MYV2 Q8MYV2

    Gene LinkOut

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