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    cype cyclope [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 46040, updated on 17-Dec-2024

    Summary

    Official Symbol
    cypeprovided by FlyBase
    Official Full Name
    cyclopeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0015031
    Locus tag
    Dmel_CG14028
    See related
    AllianceGenome:FB:FBgn0015031
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH04604; CG14028; CG18323; Cox6c; COX6C; COXH; COXVIc; cyc; Cyc; Cype; Dmel\CG14028; l(2)03771; Q9VMS1; VIc
    Summary
    Located in mitochondrion. Is expressed in several structures, including adult head; adult heart; germarium; germline cell; and imaginal disc. Used to study cytochrome-c oxidase deficiency disease. Orthologous to human COX6C (cytochrome c oxidase subunit 6C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See cype in Genome Data Viewer
    Location:
    25D6-25D6; 2-16 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5327227..5327969)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5327227..5327969)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nuclear receptor coactivator 6 Neighboring gene long non-coding RNA:CR44985 Neighboring gene uncharacterized protein Neighboring gene Turandot M

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cyclope
    Names
    CG14028-PA
    CG14028-PB
    CG14028-PC
    cype-PA
    cype-PB
    cype-PC
    cytochrome c oxidase VIc
    cytochrome c oxidase polypeptide VIc
    cytochrome c oxidase subunit 6C
    subunit VIc

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5327227..5327969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258957.2NP_001245886.1  cyclope, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245886.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95UT3, Q9VMS1
      Conserved Domains (1) summary
      cd00927
      Location:877
      Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
    2. NM_080526.3NP_536787.1  cyclope, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_536787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95UT3, Q9VMS1
      Related
      FBpp0078707
      Conserved Domains (1) summary
      cd00927
      Location:877
      Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
    3. NM_001258956.2NP_001245885.1  cyclope, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245885.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95UT3, Q9VMS1
      Conserved Domains (1) summary
      cd00927
      Location:877
      Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...