U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Acp24A4 Accessory gland protein 24A4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318936, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Acp24A4provided by FlyBase
    Official Full Name
    Accessory gland protein 24A4provided by FlyBase
    Primary source
    FLYBASE:FBgn0051779
    Locus tag
    Dmel_CG31779
    See related
    AllianceGenome:FB:FBgn0051779
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31779; Dmel\CG31779
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Involved in sexual reproduction. Located in extracellular space. Orthologous to human EPPIN-WFDC6 (EPPIN-WFDC6 readthrough) and EPPIN (epididymal peptidase inhibitor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Acp24A4 in Genome Data Viewer
    Location:
    24B1-24B1; 2-10 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3693184..3693905, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3693184..3693905, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Rapid evolution of genomic Acp complement in the melanogaster subgroup of Drosophila. Begun DJ, et al. Mol Biol Evol, 2005 Oct. PMID 15987879
    2. Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals. Mohorianu I, et al. RNA, 2017 Jul. PMID 28428330, Free PMC Article
    3. Identification and function of proteolysis regulators in seminal fluid. Laflamme BA, et al. Mol Reprod Dev, 2013 Feb. PMID 23109270, Free PMC Article
    4. Proteomics reveals novel Drosophila seminal fluid proteins transferred at mating. Findlay GD, et al. PLoS Biol, 2008 Jul 29. PMID 18666829, Free PMC Article
    5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    accessory gland protein 24A4
    Names
    Acp24A4-PB
    Acp24A4-PC
    CG31779-PB
    CG31779-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3693184..3693905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258928.2 → NP_001245857.1  accessory gland protein 24A4, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245857.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q45WF5, Q4V621
      Conserved Domains (1) summary
      pfam00014
      Location:24 → 77
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

    2. NM_001042865.1 → NP_001036330.1  accessory gland protein 24A4, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036330.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q45WF5, Q4V621
      Conserved Domains (1) summary
      pfam00014
      Location:24 → 77
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q45WF1 Q45WF1
    Q45WF3 Q45WF3
    Q45WF5 Q45WF5
    Q45WF6 Q45WF6
    Q4V621 Q4V621

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools