mip120 Myb-interacting protein 120 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mip120provided by FlyBase
Official Full Name: Myb-interacting protein 120provided by FlyBase
Primary source: FLYBASE:FBgn0033846
Locus tag: Dmel_CG6061
See related: AllianceGenome:FB:FBgn0033846
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6061; Dmel\CG6061; l(3)L4569; Mip120; MIP120; p120
Summary: Enables DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; oogenesis; and spermatogenesis. Located in chromatin. Part of DRM complex and Myb complex. Is active in nucleus. Is expressed in organism and spermatozoon. Orthologous to several human genes including LIN54 (lin-54 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (13506430..13513112)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (9393935..9400617)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in eggshell chorion gene amplification	IC Inferred by Curator more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in oogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of DRM complex	IDA Inferred from Direct Assay more info	PubMed
part_of Myb complex	IDA Inferred from Direct Assay more info	PubMed
located_in chromatin	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IDA Inferred from Direct Assay more info	PubMed

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain