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    Ir47a Ionotropic receptor 47a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36095, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ir47aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 47aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033515
    Locus tag
    Dmel_CG12900
    See related
    AllianceGenome:FB:FBgn0033515
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    47a; CG12900; DmelIR47a; Dmel\CG12900; IR47a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in gustatory receptor neurons; labellar taste bristle; proboscis; and tarsal segment. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir47a in Genome Data Viewer
    Location:
    47A2-47A2; 2-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10377128..10380109, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6264633..6267614, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene slowpoke 2 Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 47a Neighboring gene Ionotropic receptor 47b Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Taste coding of heavy metal ion-induced avoidance in Drosophila. Li X, et al. iScience, 2023 May 19. PMID 37128604, Free PMC Article
    2. Evolution of fatty acid taste in drosophilids. Dey M, et al. Cell Rep, 2023 Oct 31. PMID 37864792, Free PMC Article
    3. Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila. Dweck HKM, et al. Curr Biol, 2022 Apr 25. PMID 35294865, Free PMC Article
    4. Binding of SU(VAR)3-9 Partially Depends on SETDB1 in the Chromosomes of Drosophila melanogaster. Maksimov DA, et al. Cells, 2019 Sep 5. PMID 31491894, Free PMC Article
    5. Tastant-receptor interactions: insights from the fruit fly. Arntsen C, et al. Front Nutr, 2024. PMID 38665300, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 47a
    Names
    CG12900-PA
    Ir47a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10377128..10380109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136736.1 → NP_610580.1  ionotropic receptor 47a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610580.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z882
      Related
      FBpp0087414, FBtr0088323
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z882 A1Z882

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