lva lava lamp [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: lvaprovided by FlyBase
Official Full Name: lava lampprovided by FlyBase
Primary source: FLYBASE:FBgn0029688
Locus tag: Dmel_CG6450
See related: AllianceGenome:FB:FBgn0029688
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ABP2; CG#6450; CG6450; Dmel\CG6450; lava; Lava; Lva; LVA; LVA_DROME; lvl; Lvl
Summary: Enables microtubule binding activity. Involved in cellularization; establishment of Golgi localization; and positive regulation of dendrite morphogenesis. Located in Golgi cis cisterna. Is expressed in adult head; larval neuroblast; spermatocyte; and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (3955543..3965327, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (3849576..3859360, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables spectrin binding	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in actomyosin structure organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellularization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellularization	TAS Traceable Author Statement more info	PubMed
involved_in establishment of Golgi localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of dendrite morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi apparatus	TAS Traceable Author Statement more info	PubMed
located_in Golgi cis cisterna	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of myosin II complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in myosin filament	IBA Inferred from Biological aspect of Ancestor more info

Names: CG6450-PC; CG6450-PD; LAVA LAMP; Lava-Lamp; actin-binding protein 2; lavalamp; lva-PC; lva-PD

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The following sections contain reference sequences that belong to a specific genome build. Explain