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    Ankrd44 ankyrin repeat domain 44 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301415, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd44provided by RGD
    Official Full Name
    ankyrin repeat domain 44provided by RGD
    Primary source
    RGD:1561893
    See related
    EnsemblRapid:ENSRNOG00000021384 AllianceGenome:RGD:1561893
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561893
    Summary
    Predicted to be located in membrane. Orthologous to human ANKRD44 (ankyrin repeat domain 44). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 233.8), Thymus (RPKM 192.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd44 in Genome Data Viewer
    Location:
    9q31
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (63621193..63921999, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (56126746..56427661, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (61229252..61529532, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 2 open reading frame 66 Neighboring gene post-GPI attachment to proteins inositol deacylase 1 Neighboring gene uncharacterized LOC108351932 Neighboring gene transmembrane protein 258 B Neighboring gene ribosomal protein L11, pseudogene 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191807.5 → NP_001178736.3  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      F1LZH9
      Related
      ENSRNOP00000070078.3, ENSRNOT00000078800.3
      Conserved Domains (5) summary
      cd00204
      Location:134 → 259
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00023
      Location:272 → 304
      Ank; Ankyrin repeat
      pfam12796
      Location:177 → 269
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:532 → 587
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:140 → 170
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      63621193..63921999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017596351.3 → XP_017451840.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1

      UniProtKB/TrEMBL
      A0A8I6AGL0

    2. XM_039083293.2 → XP_038939221.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X2

      Conserved Domains (5) summary
      PHA02874
      Location:290 → 607
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:86 → 359
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:140 → 170
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:600 → 654
      Ank_4; Ankyrin repeats (many copies)
      pfam12796
      Location:12 → 104
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_039083295.2 → XP_038939223.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X3

      Related
      ENSRNOP00000091674.2, ENSRNOT00000101355.2
      Conserved Domains (5) summary
      PHA02874
      Location:323 → 625
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:86 → 359
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:140 → 170
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:961 → 991
      Ank; Ankyrin repeat
      pfam12796
      Location:622 → 718
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

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