Vha14-1 Vacuolar H[+] ATPase 14kD subunit 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Vha14-1provided by FlyBase
Official Full Name: Vacuolar H[+] ATPase 14kD subunit 1provided by FlyBase
Primary source: FLYBASE:FBgn0262512
Locus tag: Dmel_CG8210
See related: AllianceGenome:FB:FBgn0262512
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ATP6V1F; ATPase; CG8210; Dmel\CG8210; l(2)SH1248; l(2)SH2 1248; VAF1_DROME; vha14; Vha14; vha14-1
Summary: Predicted to contribute to proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Part of plasma membrane proton-transporting V-type ATPase complex. Is expressed in adult abdomen; adult head; adult heart; and adult thorax. Orthologous to human ATP6V1F (ATPase H+ transporting V1 subunit F). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (15679426..15680084, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (11566931..11567589, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to proton-transporting ATPase activity, rotational mechanism	IC Inferred by Curator more info	PubMed
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proton transmembrane transport	IC Inferred by Curator more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of plasma membrane proton-transporting V-type ATPase complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of proton-transporting V-type ATPase, V1 domain	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase, V1 domain	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG8210-PA; F subunit; V-ATPase 14kD subunit; V-ATPase proton pump; Vha14-1-PA; lethal (2) SH1248; vacuolar H[+] ATPase 14kD subunit; vacuolar H[+] ATPase subunit 14-1

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The following sections contain reference sequences that belong to a specific genome build. Explain