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    D19B D19B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38717, updated on 9-Dec-2024

    Summary

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    Official Symbol
    D19Bprovided by FlyBase
    Official Full Name
    D19Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0022699
    Locus tag
    Dmel_CG10270
    See related
    AllianceGenome:FB:FBgn0022699
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10270; d19b; Dmel\CG10270
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See D19B in Genome Data Viewer
    Location:
    65A7-65A7; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6182176..6184920, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6175276..6178020, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene fiery mountain Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene D19A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila. Bonchuk A, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33638995, Free PMC Article
    2. Identification of chromatin-associated regulators of MSL complex targeting in Drosophila dosage compensation. Larschan E, et al. PLoS Genet, 2012. PMID 22844249, Free PMC Article
    3. Genomic expansion and clustering of ZAD-containing C2H2 zinc-finger genes in Drosophila. Chung HR, et al. EMBO Rep, 2002 Dec. PMID 12446571, Free PMC Article
    4. Enhancer modeling uncovers transcriptional signatures of individual cardiac cell states in Drosophila. Busser BW, et al. Nucleic Acids Res, 2015 Feb 18. PMID 25609699, Free PMC Article
    5. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    D19B
    Names
    CG10270-PA
    D19B-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6182176..6184920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057949.5 → NP_477297.1  D19B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477297.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18387, Q9VRV4
      Related
      FBpp0076725
      Conserved Domains (4) summary
      smart00868
      Location:12 → 83
      zf-AD; Zinc-finger associated domain (zf-AD)
      COG5048
      Location:347 → 512
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:586 → 607
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:627 → 652
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O18387 O18387
    Q9VRV4 Q9VRV4

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