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    Bfc Booster for Crq [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38138, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bfcprovided by FlyBase
    Official Full Name
    Booster for Crqprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035196
    Locus tag
    Dmel_CG9129
    See related
    AllianceGenome:FB:FBgn0035196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bfc; CG9129; Dmel\CG9129
    Summary
    Enables DNA-binding transcription factor binding activity and nuclear receptor coactivator activity. Involved in positive regulation of DNA-templated transcription. Part of RNA polymerase II transcription regulator complex. Is active in nucleus. Is expressed in antennal disc; eye disc; leg disc; and wing disc. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Bfc in Genome Data Viewer
    Location:
    61F4-61F4; 3-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1250696..1251778)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1250696..1251778)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Partner of Sld Five 1 Neighboring gene Sac1 phosphatase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene triforce

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. bfc, a novel serpent co-factor for the expression of croquemort, regulates efferocytosis in Drosophila melanogaster. Zheng Q, et al. PLoS Genet, 2021 Dec. PMID 34860835, Free PMC Article
    2. Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster. Wei HC, et al. Genome, 2003 Dec. PMID 14663523
    3. New components of Drosophila leg development identified through genome wide association studies. Grubbs N, et al. PLoS One, 2013. PMID 23560084, Free PMC Article
    4. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables nuclear receptor coactivator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of positive regulation of apoptotic cell clearance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    booster for Crq
    Names
    Bfc-PA
    CG9129-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1250696..1251778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138244.3 → NP_612088.2  booster for Crq [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612088.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T3Y3, Q9W0I5
      Related
      FBpp0072547
      Conserved Domains (1) summary
      pfam14924
      Location:70 → 205
      DUF4497; Protein of unknown function (DUF4497)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3Y3 Q8T3Y3
    Q9W0I5 Q9W0I5
    Q9W0I5.2

    Gene LinkOut

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