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    [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850848, updated on 9-Dec-2024

    Summary

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    Primary source
    SGD:S000006699
    Locus tag
    YNCL0009C
    See related
    AllianceGenome:SGD:S000006699
    Gene type
    tRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translational elongation. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XII
    Sequence:
    Chromosome: XII; NC_001144.5 (448650..448721, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene acetate--CoA ligase ACS2 Neighboring gene Rnh203p Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene 25S ribosomal RNA Neighboring gene Tar1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae. Biswas M, et al. Mol Cell Biol, 2009 May. PMID 19289503, Free PMC Article
    2. Loss of anticodon wobble uridine modifications affects tRNA(Lys) function and protein levels in Saccharomyces cerevisiae. Klassen R, et al. PLoS One, 2015. PMID 25747122, Free PMC Article
    3. Functional importance of Ψ38 and Ψ39 in distinct tRNAs, amplified for tRNAGln(UUG) by unexpected temperature sensitivity of the s2U modification in yeast. Han L, et al. RNA, 2015 Feb. PMID 25505024, Free PMC Article
    4. Saccharomyces cerevisiae imports the cytosolic pathway for Gln-tRNA synthesis into the mitochondrion. Rinehart J, et al. Genes Dev, 2005 Mar 1. PMID 15706032, Free PMC Article
    5. A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. Björk GR, et al. RNA, 2007 Aug. PMID 17592039, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables triplet codon-amino acid adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

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