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    HXT14 Hxt14p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855398, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HXT14
    Official Full Name
    Hxt14p
    Primary source
    SGD:S000005262
    Locus tag
    YNL318C
    See related
    AllianceGenome:SGD:S000005262; FungiDB:YNL318C; VEuPathDB:YNL318C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables galactose transmembrane transporter activity. Involved in hexose transmembrane transport. Located in cell periphery; fungal-type vacuole; and mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HXT14 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (38707..40329, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Vnx1p Neighboring gene uncharacterized protein Neighboring gene cleavage polyadenylation factor subunit PFS2 Neighboring gene prephenate dehydratase PHA2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Design and engineering of intracellular-metabolite-sensing/regulation gene circuits in Saccharomyces cerevisiae. Wang M, et al. Biotechnol Bioeng, 2016 Jan. PMID 26059511
    2. Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. Wieczorke R, et al. FEBS Lett, 1999 Dec 31. PMID 10618490
    3. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. Kyriakou D, et al. BMC Biol, 2016 Dec 7. PMID 27927215, Free PMC Article
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
    5. The proteome of Saccharomyces cerevisiae mitochondria. Sickmann A, et al. Proc Natl Acad Sci U S A, 2003 Nov 11. PMID 14576278, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in galactose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hexose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Hxt14p
    NP_014081.1
    • Protein with similarity to hexose transporter family members; expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      38707..40329 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183156.1 → NP_014081.1  TPA: Hxt14p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014081.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0M7, P42833
      UniProtKB/TrEMBL
      A6ZSG2, C7GWR5, C8ZGK7, G2WLF1, N1NXQ9
      Conserved Domains (1) summary
      cd17356
      Location:62 → 537
      MFS_HXT; Fungal Hexose transporter subfamily of the Major Facilitator Superfamily of transporters and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42833.2

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