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    Enoph Enolase-phosphatase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40630, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Enophprovided by FlyBase
    Official Full Name
    Enolase-phosphataseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037305
    Locus tag
    Dmel_CG12173
    See related
    AllianceGenome:FB:FBgn0037305
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    24644163; CG12173; Dmel\CG12173; ENOPH
    Summary
    Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Orthologous to human ENOPH1 (enolase-phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Enoph in Genome Data Viewer
    Location:
    82F7-82F7; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5255444..5256681, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1081166..1082403, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cathepsin F Neighboring gene antisense RNA:CR44019 Neighboring gene uncharacterized protein Neighboring gene Tim17a2 Neighboring gene HIF prolyl hydroxylase Neighboring gene long non-coding RNA:CR45793

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng). Liu QX, et al. J Ginseng Res, 2018 Jul. PMID 29983616, Free PMC Article
    2. Abdominal-B neurons control Drosophila virgin female receptivity. Bussell JJ, et al. Curr Biol, 2014 Jul 21. PMID 24998527, Free PMC Article
    3. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
    4. A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses. Dubruille R, et al. PLoS Genet, 2009 Dec. PMID 20041201, Free PMC Article
    5. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acireductone synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acireductone synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-methionine salvage from methylthioadenosine IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Enolase-phosphatase
    Names
    CG12173-PA
    Enoph-PA
    NP_649523.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5255444..5256681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141266.3 → NP_649523.1  Enolase-phosphatase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649523.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V3F1, Q9VN95
      UniProtKB/TrEMBL
      Q4V565
      Related
      FBpp0078463
      Conserved Domains (2) summary
      TIGR01691
      Location:8 → 244
      enolase-ppase; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
      pfam13419
      Location:11 → 217
      HAD_2; Haloacid dehalogenase-like hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VN95.2 Q9VN95

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