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    CG14866 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41854, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14866provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038315
    Locus tag
    Dmel_CG14866
    See related
    AllianceGenome:FB:FBgn0038315
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14866
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including embryonic epipharynx; embryonic head epidermis; embryonic head sensory system; embryonic/larval tracheal section; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14866 in Genome Data Viewer
    Location:
    88F1-88F1; 3-57 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15316471..15318285)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11142193..11144007)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Tropomyosin 1 Neighboring gene uncharacterized protein Neighboring gene Tropomyosin 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ENL/AF9-related

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Dodd RB, et al. Glycobiology, 2001 May. PMID 11425795
    2. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718
    3. Participation of a galactose-specific C-type lectin in Drosophila immunity. Tanji T, et al. Biochem J, 2006 May 15. PMID 16475980, Free PMC Article
    4. Trachealess (Trh) regulates all tracheal genes during Drosophila embryogenesis. Chung S, et al. Dev Biol, 2011 Dec 1. PMID 21963537, Free PMC Article
    5. Genome-scale functional characterization of Drosophila developmental enhancers in vivo. Kvon EZ, et al. Nature, 2014 Aug 7. PMID 24896182

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14866-PA
    CG14866-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15316471..15318285
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142187.3 → NP_650444.1  uncharacterized protein Dmel_CG14866, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650444.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VF94
      Related
      FBpp0082537
      Conserved Domains (1) summary
      smart00034
      Location:194 → 357
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)

    2. NM_001144585.2 → NP_001138057.1  uncharacterized protein Dmel_CG14866, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138057.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z0K3
      Conserved Domains (1) summary
      smart00034
      Location:271 → 434
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z0K3 B7Z0K3
    Q9VF94 Q9VF94

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