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    Archease archease [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42551, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Archeaseprovided by FlyBase
    Official Full Name
    archeaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0289108
    Locus tag
    Dmel_CG6353
    See related
    AllianceGenome:FB:FBgn0289108
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Arch; BcDNA:SD28072; CG6353; disjointed; Disjointed; Dmel\CG6353; dsj
    Summary
    Involved in positive regulation of axon regeneration and tRNA processing. Predicted to be part of tRNA-splicing ligase complex. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Archease in Genome Data Viewer
    Location:
    93F1-93F2; 3-73 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21661186..21662972, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17486908..17488694, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene E2F transcription factor 1 Neighboring gene long non-coding RNA:CR46056 Neighboring gene long non-coding RNA:CR46057 Neighboring gene Juvenile hormone binding protein 16 Neighboring gene DNA polymerase alpha subunit 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of Archease by the mTOR-vATPase axis. Francis D, et al. Development, 2022 Oct 1. PMID 36111596, Free PMC Article
    2. Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia. Schmidt CA, et al. Biol Open, 2022 Mar 15. PMID 35132432, Free PMC Article
    3. Regulation of axon regeneration by the RNA repair and splicing pathway. Song Y, et al. Nat Neurosci, 2015 Jun. PMID 25961792, Free PMC Article
    4. Models of axon regeneration in Drosophila. Brace EJ, et al. Exp Neurol, 2017 Jan. PMID 26996133, Free PMC Article
    5. Molecular determinants of metazoan tricRNA biogenesis. Schmidt CA, et al. Nucleic Acids Res, 2019 Jul 9. PMID 31032518, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of axon regeneration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of tRNA-splicing ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    archease
    Names
    Archease-PA
    CG6353-PA
    disjointed

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21661186..21662972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142718.2 → NP_650975.1  archease [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650975.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86P43, Q9VD92
      UniProtKB/TrEMBL
      H0RNK8
      Related
      FBpp0083515
      Conserved Domains (1) summary
      pfam01951
      Location:17 → 156
      Archease; Archease protein family (MTH1598/TM1083)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VD92.1 Q9VD92

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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