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    ATP19 F1F0 ATP synthase subunit k [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854077, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ATP19
    Official Full Name
    F1F0 ATP synthase subunit k
    Primary source
    SGD:S000007339
    Locus tag
    YOL077W-A
    See related
    AllianceGenome:SGD:S000007339; FungiDB:YOL077W-A; VEuPathDB:YOL077W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Involved in protein-containing complex assembly and proton motive force-driven ATP synthesis. Part of proton-transporting ATP synthase complex, coupling factor F(o). Is active in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ATP19 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (185438..185644)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene putative 3'-5' exonuclease Neighboring gene Avo1p Neighboring gene ribosome biogenesis protein BRX1 Neighboring gene Mdm20p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stepwise assembly of dimeric F(1)F(o)-ATP synthase in mitochondria involves the small F(o)-subunits k and i. Wagner K, et al. Mol Biol Cell, 2010 May 1. PMID 20219971, Free PMC Article
    2. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. Kemmer D, et al. BMC Microbiol, 2009 Jan 14. PMID 19144191, Free PMC Article
    3. Yeast mitochondrial F1F0-ATP synthase exists as a dimer: identification of three dimer-specific subunits. Arnold I, et al. EMBO J, 1998 Dec 15. PMID 9857174, Free PMC Article
    4. Atomic model for the dimeric F(O) region of mitochondrial ATP synthase. Guo H, et al. Science, 2017 Nov 17. PMID 29074581, Free PMC Article
    5. Comparison between single-molecule and X-ray crystallography data on yeast F1-ATPase. Steel BC, et al. Sci Rep, 2015 Mar 10. PMID 25753753, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that Su k (Atp19) and Su i (Atp18) are involved in the assembly of Su e (Atp21) and Su g (Atp20) F(1)F(o)-ATP synthase dimers and oligomers.
      Title: Stepwise assembly of dimeric F(1)F(o)-ATP synthase in mitochondria involves the small F(o)-subunits k and i.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ATP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein-containing complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton motive force-driven ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F1F0 ATP synthase subunit k
    NP_014564.1
    • Subunit k of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      185438..185644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184377.1 → NP_014564.1  TPA: F1F0 ATP synthase subunit k [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014564.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1Z0, P81451
      UniProtKB/TrEMBL
      A6ZND3, B3LIY4, C7GK43, C8ZHN9, G2WMF7, N1P418
      Conserved Domains (1) summary
      pfam11022
      Location:4 → 65
      DUF2611; Protein of unknown function (DUF2611)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P81451.1

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