U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG6028 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42589, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG6028provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038924
    Locus tag
    Dmel_CG6028
    See related
    AllianceGenome:FB:FBgn0038924
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6028
    Summary
    Predicted to enable acetylpyruvate hydrolase activity. Is expressed in several structures, including Malpighian tubule primordium; adult head; adult heart; embryonic/larval midgut primordium; and gut section. Orthologous to human FAHD2A (fumarylacetoacetate hydrolase domain containing 2A) and FAHD2B (fumarylacetoacetate hydrolase domain containing 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG6028 in Genome Data Viewer
    Location:
    94A1-94A1; 3-74 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22024259..22025506, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17849981..17851228, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Isocitrate dehydrogenase 3b Neighboring gene mitofilin Neighboring gene mitochondrial ribosomal protein L35 Neighboring gene Cytochrome c heme lyase Neighboring gene NADH dehydrogenase (ubiquinone) 42 kDa subunit

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Unraveling the protective effect of a Drosophila phosphatidylethanolamine-binding protein upon bacterial infection by means of proteomics. Reumer A, et al. Dev Comp Immunol, 2009 Nov. PMID 19545586
    2. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. Azad P, et al. G3 (Bethesda), 2012 Oct. PMID 23050227, Free PMC Article
    3. Characteristics of genes up-regulated and down-regulated after 24 h starvation in the head of Drosophila. Fujikawa K, et al. Gene, 2009 Oct 1. PMID 19573582
    4. In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor. Baker FC, et al. Development, 2021 Nov 15. PMID 35020877, Free PMC Article
    5. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetylpyruvate hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in oxaloacetate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG6028-PA
    NP_651002.3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22024259..22025506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142745.4 → NP_651002.3  uncharacterized protein Dmel_CG6028 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651002.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SI7, Q9VD56
      Related
      FBpp0083584
      Conserved Domains (2) summary
      COG0179
      Location:37 → 293
      MhpD; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport and catabolism]
      pfam01557
      Location:86 → 290
      FAA_hydrolase; Fumarylacetoacetate (FAA) hydrolase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95SI7 Q95SI7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools