U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    vls valois [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35289, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    vlsprovided by FlyBase
    Official Full Name
    valoisprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003978
    Locus tag
    Dmel_CG10728
    See related
    AllianceGenome:FB:FBgn0003978
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    38B.5; CG107278; CG10728; Dmel\CG10728; dWD45; val; Vls
    Summary
    Involved in pole plasm assembly. Located in P granule. Is expressed in several structures, including anlage in statu nascendi; antennal anlage; antennal primordium; embryonic/larval midgut primordium; and head epidermis primordium. Orthologous to human WDR77 (WD repeat domain 77). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See vls in Genome Data Viewer
    Location:
    38B2-38B2; 2-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20064261..20065679, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20064261..20065679, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene short neuropeptide F precursor Neighboring gene barren Neighboring gene loki Neighboring gene antisense RNA:CR44907 Neighboring gene brain washing Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment. Oishi I, et al. Mech Dev, 1998 Feb. PMID 9507063
    2. Arginine methylation of vasa protein is conserved across phyla. Kirino Y, et al. J Biol Chem, 2010 Mar 12. PMID 20080973, Free PMC Article
    3. Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity. Hay B, et al. Development, 1990 Jun. PMID 2119289
    4. Requirements for scribble expression in newly formed gonads of Drosophila embryos. Marhold J, et al. Gene Expr Patterns, 2003 May. PMID 12711540
    5. Targeting and anchoring Tudor in the pole plasm of the Drosophila oocyte. Anne J. PLoS One, 2010 Dec 15. PMID 21179512, Free PMC Article

    See all (111) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellularization HMP PubMed 
    involved_in embryonic pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oocyte axis specification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pole plasm assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pole plasm assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in pole plasm assembly TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of methylosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in pole plasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    valois
    Names
    CG10728-PA
    vls-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20064261..20065679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136175.5 → NP_610019.2  valois [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610019.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95SA0, Q9VIP8
      UniProtKB/TrEMBL
      B5RIR0
      Related
      FBpp0080879
      Conserved Domains (3) summary
      COG2319
      Location:134 → 358
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:157 → 198
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:106 → 282
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIP8.1 Q9VIP8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous