Pold3 DNA polymerase delta 3, accessory subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pold3provided by RGD
Official Full Name: DNA polymerase delta 3, accessory subunitprovided by RGD
Primary source: RGD:1312027
See related: EnsemblRapid:ENSRNOG00000018411 AllianceGenome:RGD:1312027
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to DNA-directed DNA polymerase activity. Involved in DNA-templated DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of delta DNA polymerase complex and zeta DNA polymerase complex. Orthologous to human POLD3 (DNA polymerase delta 3, accessory subunit). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 127.6), Thymus (RPKM 111.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q32

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (163830217..163870015, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (154417893..154456687, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (165085142..165122385, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

AU046732 (e-PCR)
- UniSTS:111184

RH137658 (e-PCR)
- UniSTS:219745

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
contributes_to DNA-directed DNA polymerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in DNA biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in DNA strand elongation involved in DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA synthesis involved in UV-damage excision repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA-templated DNA replication	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in DNA-templated DNA replication	ISO Inferred from Sequence Orthology more info
involved_in error-prone translesion synthesis	ISO Inferred from Sequence Orthology more info
involved_in nucleotide-excision repair, DNA gap filling	IBA Inferred from Biological aspect of Ancestor more info
involved_in nucleotide-excision repair, DNA gap filling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of delta DNA polymerase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of delta DNA polymerase complex	IC Inferred by Curator more info	PubMed
part_of delta DNA polymerase complex	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of zeta DNA polymerase complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: DNA polymerase delta subunit 3

Names: DNA-directed DNA polymerase delta 3; polymerase (DNA) delta 3, accessory subunit; polymerase (DNA-directed), delta 3, accessory subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.